# Can Glucophage XR (metformin extended-release) be crushed?

Canonical: [https://followyourswallow.com/medications/can-i-crush-metformin-extended-release](https://followyourswallow.com/medications/can-i-crush-metformin-extended-release)

## Direct answer

**NO. Do not crush.** Glucophage XR, Fortamet, and Glumetza are all on the ISMP “Do Not Crush” list as extended-release tablets, and FDA labeling states Glucophage XR must be swallowed whole and never crushed or chewed. Crushing destroys the slow-release mechanism.

Formulation: Extended-release tablet

## What to ask the pharmacist

Ask the pharmacist whether switching to immediate-release metformin tablets or a metformin oral solution is an option.

## Verification

- Source type: ISMP Do Not Crush guidance
- Source note: ISMP “Do Not Crush” list; FDA labeling: swallow whole
- Source checked: 2026-06-10


## Safety

Confirm with your pharmacist before changing how any medication is taken. Match the exact drug, strength, dosage form, release mechanism, manufacturer or NDC, and imprint. A pill image alone is not enough.