# Can Seroquel XR (quetiapine extended-release) be crushed?

Canonical: [https://followyourswallow.com/medications/can-i-crush-quetiapine-extended-release](https://followyourswallow.com/medications/can-i-crush-quetiapine-extended-release)

## Direct answer

**NO. Do not crush.** FDA-submitted labeling says quetiapine extended-release tablets should be swallowed whole and must not be split, chewed, or crushed.

Formulation: Extended-release tablet

## What to ask the pharmacist

Ask the pharmacist or prescriber whether a different formulation or medication plan is appropriate for someone who cannot swallow the XR tablet whole.

## Verification

- Source type: FDA labeling
- Source note: Current DailyMed FDA-submitted quetiapine extended-release labeling
- Source checked: 2026-08-05


Source: [Primary medication source](https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=67872105-4ec6-4d46-b3b4-c672c93576d2&version=1)

## Safety

Confirm with your pharmacist before changing how any medication is taken. Match the exact drug, strength, dosage form, release mechanism, manufacturer or NDC, and imprint. A pill image alone is not enough.