# Can Zoloft (sertraline) be crushed?

Canonical: [https://followyourswallow.com/medications/can-i-crush-sertraline](https://followyourswallow.com/medications/can-i-crush-sertraline)

## Direct answer

**YES. Generally crushable.** Sertraline tablets are immediate-release; they do not appear on the ISMP “Do Not Crush” list and FDA labeling contains no restriction against crushing.

Formulation: Immediate-release film-coated tablet

## What to ask the pharmacist

Ask the pharmacist about the FDA-approved sertraline oral concentrate, which must be diluted as directed in the label before use.

## Verification

- Source type: FDA labeling
- Source note: FDA labeling (no crush restriction); not on ISMP “Do Not Crush” list
- Source checked: 2026-06-10


## Safety

Confirm with your pharmacist before changing how any medication is taken. Match the exact drug, strength, dosage form, release mechanism, manufacturer or NDC, and imprint. A pill image alone is not enough.