Medication module
Can Eliquis (apixaban) be crushed?
Also searched as Eliquis · Immediate-release film-coated tablet
Exact formulation checkedImmediate-release film-coated tabletA different strength, suffix, coating, capsule, or manufacturer may have different instructions.
Why
FDA labeling explicitly states that for patients unable to swallow whole tablets, Eliquis tablets may be crushed and suspended in water, D5W, or apple juice, or mixed with applesauce and promptly administered; crushed tablets are stable in these vehicles for up to 4 hours.
What to ask the pharmacist instead
Ask the pharmacist to review the label's approved mixing liquids and the requirement to take the crushed mixture promptly.
Source checked2026-08-05
Clinical reviewSLP review in progress
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.
Confirm the pill before changing it
- Match the generic or brand name and strength on the prescription label.
- Match the exact formulation, especially ER, XR, XL, SR, CR, DR, or EC.
- Use the manufacturer or NDC and imprint as supporting identifiers, then confirm with the pharmacist.
Do not use color or shape alone. FDA guidance notes that approved generic pills can look different while containing the same medicine.
Keep going