Medication module
Can I crush this?
Search 35 formulation-specific answers drawn only from the ISMP “Do Not Crush” list and FDA labeling. Crushing the wrong pill can be dangerous. Check every medication, every time.
35 formulations
acetaminophenTylenol (immediate-release tablets) · Immediate-release tabletYESoxycodone extended-releaseOxyContin · Extended-release tablet (abuse-deterrent)NOomeprazole delayed-releasePrilosec · Delayed-release capsuleCHECKmetoprolol succinate ERToprol-XL · Extended-release tablet (scored)CHECKaspirin enteric-coatedEcotrin, Bayer Safety Coated · Enteric-coated tabletNOmetformin immediate-releaseGlucophage · Immediate-release tabletYESmetformin extended-releaseGlucophage XR, Fortamet, Glumetza · Extended-release tabletNOlevothyroxineSynthroid, Levo-T, Unithroid · Immediate-release tabletYESamlodipineNorvasc · Immediate-release tabletYESlisinoprilZestril, Prinivil · Immediate-release tabletYESatorvastatinLipitor · Immediate-release film-coated tabletYESgabapentin (immediate-release capsules)Neurontin · Immediate-release capsuleYESdonepezil (5 mg and 10 mg)Aricept · Immediate-release film-coated tabletYESdonepezil 23 mgAricept 23 mg · Film-coated tablet (modified absorption)NOalendronateFosamax · Tablet (mucous membrane irritant)NOpotassium chloride extended-releaseKlor-Con, Klor-Con M, K-Tab · Extended-release tabletNOfurosemideLasix · Immediate-release tabletYESsertralineZoloft · Immediate-release film-coated tabletYESvenlafaxine extended-releaseEffexor XR · Extended-release capsule with pelletsNOdiltiazem extended-releaseCardizem CD, Cardizem LA, Cartia XT, Tiazac · Extended-release capsule or tabletNOcarbidopa-levodopa immediate-releaseSinemet · Immediate-release tabletYEScarbidopa-levodopa extended-releaseSinemet CR, Rytary · Extended-release tablet (Sinemet CR) or capsule (Rytary)NOmemantine immediate-releaseNamenda · Immediate-release tabletYESmemantine extended-releaseNamenda XR · Extended-release capsuleNOduloxetine delayed-releaseCymbalta · Delayed-release (enteric-coated) capsuleNOapixabanEliquis · Immediate-release film-coated tabletYESclopidogrelPlavix · Immediate-release film-coated tabletYEStamsulosinFlomax · Extended-release capsuleNOpantoprazole delayed-releaseProtonix · Delayed-release tabletNOrivaroxabanXarelto · Immediate-release film-coated tabletCHECKdabigatran etexilate capsulesPradaxa · Capsule containing coated pelletsNObupropion XLWellbutrin XL · Extended-release tabletNOquetiapine extended-releaseSeroquel XR · Extended-release tabletNOdivalproex delayed-release or extended-release tabletsDepakote, Depakote ER · Delayed-release or extended-release tabletNOdivalproex sprinkle capsulesDepakote Sprinkle · Delayed-release sprinkle capsuleCHECK
Read the formulation, not just the drug name
ER · XR · XL · SR · CRThese often signal modified release. Never assume they can be crushed.
DR · ECDelayed-release and enteric coatings may protect the medicine or the stomach.
Capsules and beadsSome labels allow opening; others forbid it. The exact product decides.
Why no generic pill photos? Color and shape can vary between approved manufacturers. A photo may support an exact NDC or imprint check, but it cannot establish identity or crushability. Use the prescription label and confirm with a pharmacist. The FDA also offers an official drug-identification service ↗.