Medication module
Can Aricept 23 mg (donepezil 23 mg) be crushed?
Also searched as Aricept 23 mg · Film-coated tablet (modified absorption)
Exact formulation checkedFilm-coated tablet (modified absorption)A different strength, suffix, coating, capsule, or manufacturer may have different instructions.
Why
The ISMP “Do Not Crush” list states crushing the 23 mg tablet may significantly increase the rate of absorption, and FDA labeling says the 23 mg tablet should be swallowed whole and not split, crushed, or chewed.
What to ask the pharmacist instead
Ask the pharmacist or prescriber whether a regimen using crushable lower-strength tablets or the ODT form is appropriate instead.
SourceISMP “Do Not Crush” list; FDA labeling: do not split, crush, or chew
Source checked2026-06-10
Clinical reviewSLP review in progress
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.
Confirm the pill before changing it
- Match the generic or brand name and strength on the prescription label.
- Match the exact formulation, especially ER, XR, XL, SR, CR, DR, or EC.
- Use the manufacturer or NDC and imprint as supporting identifiers, then confirm with the pharmacist.
Do not use color or shape alone. FDA guidance notes that approved generic pills can look different while containing the same medicine.
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