Medication module
donepezil (5 mg and 10 mg)
Aricept · Immediate-release film-coated tablet
Why
The ISMP “Do Not Crush” list note for Aricept applies only to the 23 mg strength and states the 5 and 10 mg tablets are not affected. FDA labeling places the swallow-whole restriction only on the 23 mg tablet.
What to ask the pharmacist instead
Ask the pharmacist about the orally disintegrating tablet (ODT) form of donepezil as an alternative to crushing.
SourceISMP “Do Not Crush” list (only the 23 mg tablet is affected)
Clinical review2026-06-10 · pharmacist-checked
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.