Follow Your Swallow

Medication module

Can Namenda XR (memantine extended-release) be crushed?

Also searched as Namenda XR · Extended-release capsule

NO. Do not crush

Exact formulation checkedExtended-release capsuleA different strength, suffix, coating, capsule, or manufacturer may have different instructions.

Namenda XR is on the ISMP “Do Not Crush” list as extended-release, and FDA labeling states the capsule should not be divided, chewed, or crushed. The label does allow opening the capsule and sprinkling the entire contents on applesauce, swallowed without chewing.

Ask the pharmacist about the label-approved applesauce sprinkle method or the memantine oral solution as alternatives.

SourceISMP “Do Not Crush” list; FDA labeling permits sprinkle administration
Source checked2026-06-10
Clinical reviewSLP review in progress

Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.

  1. Match the generic or brand name and strength on the prescription label.
  2. Match the exact formulation, especially ER, XR, XL, SR, CR, DR, or EC.
  3. Use the manufacturer or NDC and imprint as supporting identifiers, then confirm with the pharmacist.

Do not use color or shape alone. FDA guidance notes that approved generic pills can look different while containing the same medicine.