Medication module
Can Cardizem CD (diltiazem extended-release) be crushed?
Also searched as Cardizem CD, Cardizem LA, Cartia XT, Tiazac · Extended-release capsule or tablet
Exact formulation checkedExtended-release capsule or tabletA different strength, suffix, coating, capsule, or manufacturer may have different instructions.
Why
Cardizem CD, Cardizem LA, and other extended-release diltiazem products are on the ISMP “Do Not Crush” list; crushing releases a day's worth of drug at once instead of gradually.
What to ask the pharmacist instead
Ask the pharmacist whether an immediate-release diltiazem tablet regimen or an ER capsule brand whose label allows opening and sprinkling the beads is an option.
SourceISMP “Do Not Crush” list (extended-release)
Source checked2026-06-10
Clinical reviewSLP review in progress
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.
Confirm the pill before changing it
- Match the generic or brand name and strength on the prescription label.
- Match the exact formulation, especially ER, XR, XL, SR, CR, DR, or EC.
- Use the manufacturer or NDC and imprint as supporting identifiers, then confirm with the pharmacist.
Do not use color or shape alone. FDA guidance notes that approved generic pills can look different while containing the same medicine.
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