Medication module
diltiazem extended-release
Cardizem CD, Cardizem LA, Cartia XT, Tiazac · Extended-release capsule or tablet
Why
Cardizem CD, Cardizem LA, and other extended-release diltiazem products are on the ISMP “Do Not Crush” list; crushing releases a day's worth of drug at once instead of gradually.
What to ask the pharmacist instead
Ask the pharmacist whether an immediate-release diltiazem tablet regimen or an ER capsule brand whose label allows opening and sprinkling the beads is an option.
SourceISMP “Do Not Crush” list (extended-release)
Clinical review2026-06-10 · pharmacist-checked
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.